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Gabriel Rocklin

Gabriel Rocklin's mixed computational/experimental lab develops high-throughput methods for protein biophysics and protein design, with a focus on designing protein therapeutics. Key questions include: How do protein sequence and structure determine folding stability, conformational dynamics, binding affinity, and other protein properties? Can we quantitatively predict these protein "phenotypes" from genotype (sequence) using computational modeling? And how do we design protein therapeutics that optimize these phenotypes?

Prof. Gabriel Rocklin's Website